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Publications

Sałaciak Kinga, Lustyk Klaudia, Jagielska Angelika, Szafarz Małgorzata, Inteiro-Oliveira Sara, Diógenes Maria, Xapelli Sara, Schnur Paulina, Morton Lucy, , Ferreira Jacques, , Crouzier Lucie, Meunier Johann, Delprat Benjamin, Maurice Tangui, Pytka Karolina

Neurotherapeutics Vol 23 (2026)

Byron Nicole, , Pisano Filippo, Pisanello Marco, Ferreira Jacques, Montinaro Cinzia, , De Vittorio Massimo, Pisanello Ferruccio,

Neurophotonics Vol 12 (2025)

Hawraa F R M Ali H, Somani Sukrut, , MAEYOUF Khadeejah Almabrouk Abdulsayid, , Gerasimou Symeon, Tate Rothwelle, , Mullin Margaret, , , , , ,

International Journal of Nanomedicine Vol 20, pp. 11569—11591 (2025)

, Ip Nancy Y,

Scientific Reports Vol 15 (2025)

Visocky Vladimir, Morris Brian J, Dunlop John, Brandon Nick, ,

European Journal of Neuroscience Vol 59, pp. 554-569 (2024)

eNeuro Vol 10, pp. 1-10 (2023)

Research Interests

Research Projects
1. State-dependent auditory processing and perception
When we are paying attention to sound, we can vividly perceive it. When sleep, however, our perception is siginificantly diminished. But what is happening in the brain? Because our brain activity ('brain state') continuously changes, it is extremely important to address the following three questions: 1) how is each brain state organized at the level of neural circuit? 2) how do brain states affect sensory processing and perceptual decision? and 3) how are brain states regulated? We are addressing these questions by taking multidisciplinary approaches, with a focus on dynamic interplays between the auditory system and neuromodulatory systems.

2. The circuit mechanism of abnormal hearing
Brain circuits often generate auditory perception even in the absence of auditory inputs, such as auditory hallucinations. But how? We are particularly focusing on phantom auditory perception, so-calledÌýtinnitus. Tinnitus is a symptom, which is often associated with hearing loss. Considering aging society and age-related hearing loss, a better understanding of the neural basis of tinnitus is extremly urgent. We are aiming to identify neural correlates of tinnitus at the level ofÌýneuronal circuits. By using a massively parallel extracellular recording technique and aÌýbehavioural approach, we are determining relationships between tinnitus andÌýabnormal neural population activity in the auditory thalamocortical circuit. This research program will provide further insight into the development of new treatment for tinnitus sufferers.

3. Technology development to improve and restore hearing
Once we understand both normal and abnormal states, a next step is to explore strategies to restore abnormal states into the normal one. In addition, we can also think of how we can boost our normal brain functions. To achieve these goals, we are developing new approaches and technologies. We are particularly interested in the improvement and restoration of sensory abilities by controlling neural activity. Combining advanced technologies in rodents as a model, we are developing novel strategies to improve and restore hearing.

***Our research team is currently accepting applications from prospective PhD students and postdocs. In particular, persons who have strong background in physics, mathematics, or engineering are strongly encouraged to apply. ***

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Professional Activities

Speaker

25/8/2023

Speaker

12/5/2023

Speaker

25/10/2022

Peer reviewer

2022

Speaker

13/5/2021

Peer reviewer

2021

Projects

Mathieson, Keith (Principal Investigator) Sakata, Shuzo (Co-investigator) Vladimirova, Vanesa (Research Co-investigator)

01-Jan-2024 - 01-Jan-2028

Mathieson, Keith (Principal Investigator) Sakata, Shuzo (Co-investigator) Vladimirova, Vanesa (Research Co-investigator)

01-Jan-2024 - 01-Jan-2028

Sakata, Shuzo (Principal Investigator)

01-Jan-2024 - 31-Jan-2025

Sakata, Shuzo (Principal Investigator)

01-Jan-2023 - 30-Jan-2026

McGeown, William (Principal Investigator) Parra Rodriguez, Mario (Co-investigator) Sakata, Shuzo (Co-investigator)

01-Jan-2023 - 30-Jan-2024

Bushell, Trevor (Principal Investigator) Sakata, Shuzo (Co-investigator)

01-Jan-2022 - 30-Jan-2025