Dr Arnaud Javelle
Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
Personal statement
Ion Transport in Bacteria
Research in my laboratory is focused on membrane proteins involved in transport of ions across cellular membranes and in signalling processes relating to ion availability. Studies of membrane transporters/channels have had a great impact on our understanding human disease and drug design; indeed ion channels are, at present, the third biggest target classe in drug discovery and about 30% of current clinically marked drugs are targeted against these proteins.
The philosophy of my research, is to use simple and well studied bacterial model organisms, and a multidisciplinary approach to shed more light on two ubiquitous families of ion transporters both of which are conserved from bacteria to man: the ammonium transporter from the Amt/Rh family (TC 1.A.11) and the sulphate permease from the SulP/SLC26A family (TC 2.A.53).
I am a Fellow of the Higher Education Academy.
Prize And Awards
- Recipient
- 1/10/2014
Publications
- Williamson Gordon, , Bizior Adriana, , ,
- FEBS Journal Vol 291, pp. 3786-3810 (2024)
- Fern谩ndez-Mart铆nez Lorena T, ,
- Microbiology Vol 170 (2024)
- Williamson Gordon, Bizior Adriana, , , ,
- Bioscience Reports Vol 44 (2024)
- Bizior Adriana, Williamson Gordon, , ,
- Microbiology Vol 169 (2023)
- Williamson Gordon, Brito Ana Sofia, Bizior Adriana, Tamburrino Giulia, Dias Mirandela Gaetan, , , Zachariae Ulrich, Marini Anna Maria, Boeckstaens Melanie,
- mBio Vol 13 (2022)
- Williamson Gordon, Tamburrino Giulia, Bizior Adriana, Boeckstaens M茅lanie, Dias Mirandela Ga毛tan, Bage Marcus G, Pisliakov Andrei, Ives Callum M, Terras Eilidh, , Marini Anna-Maria, Zachariae Ulrich,
- eLife Vol 11 (2022)
Professional Activities
- Speaker
- 30/4/2019
- Speaker
- 5/12/2018
- External Examiner
- 4/12/2018
- Speaker
- 8/11/2018
- Speaker
- 26/10/2018
- Speaker
- 2/7/2018
Projects
- Javelle, Arnaud (Principal Investigator) BOECKSTAENS, Melanie (Researcher)
- EMBO Short term Fellowship
The objective is to perform an in vitro assay using purified yeast mep ammonium transporter to undertake quantitative kinetic measurements under a variety of experimental condition. This assay using Solid Surface Membrane Electrophysiology (SSME) consists in measuring transport activity by electrophysiology after reconstitution of the purified transporter into artificial liposomes. - 02-Jan-2018 - 17-Jan-2018
- Javelle, Arnaud (Principal Investigator)
- Visit to Devro (Gordon Paul, Darren Quinn, Katrina Davidson for PhD studentships via IBioIC/Strathclyde CDT
- 11-Jan-2018
- Javelle, Arnaud (Principal Investigator) Gabel, Frank (Principal Investigator)
- 01-Jan-2018 - 30-Jan-2018
- Javelle, Arnaud (Principal Investigator)
- 01-Jan-2017 - 30-Jan-2018
- Javelle, Arnaud (Principal Investigator) 脺belmesser, Nadine (Post Grad Student)
- ERASMUS
- 24-Jan-2016 - 27-Jan-2017
- Javelle, Arnaud (Principal Investigator) Gabel, Frank (Research Co-investigator)
- 01-Jan-2016 - 30-Jan-2016
Contact
Dr
Arnaud
Javelle
Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
Email: arnaud.javelle@strath.ac.uk
Tel: 548 3827